Brady, 45, and Gisele Bundchen finalized their divorce after 13 years of marriage last month.
The looming split came after Gisele was reportedly unhappy when the seven-time Super Bowl champ decided not to retire and return to the gridiron.
Fans are calling for Brady and former golf star Spiranac to come together and become a powerhouse duo in the sport.
The 29-year-old, who was married to Stephen Tinoco until March 2022, responded to her fans saying she loves trying to “make someone’s day better.”
A tweet from a follower of Spiranac read: “If I were Tom Brady, I would call PaigeSpiranac. 29, incredibly hot, recently divorced and former professional athlete who understands and supports what he does for a living.
“And Brady loves to play golf. Now that would be a power couple.”
Others praised Spiranac as “a very nice person,” to which the American replied, “You guys are very nice, thank you!
“It takes no effort to be nice, so I always try to do my part to make someone’s day better.”
Spiranac is undoubtedly an eye-catcher, often stunning fans on her social media platforms with racy photos.
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And according to GolfMagic, she has overtaken golf legends including Tiger Woods, Phil Mickelson and Rory McIlroy to take the lead as the most followed golfer.
Spiranac has said that such fan interactions rank high among the best things about her fame.
Spiranac told Betsperts: “The best part of my job is being able to communicate with so many people around the world.
“I’ve had some amazing interactions with my followers sharing stories about how I’ve helped them with their mental health or parents talking about how they got their daughters into golf.
“I played this event in Tahoe which was very male-dominated. I was 1 of 4 women playing.
“There were these two little girls on the course and I ended up taking a picture with them.
“The next day, their grandfather was my scorer, and he said the little girls were dying to play golf now because of that moment. It meant a lot.”